Edition 01 · live now
Every Sunday, three of the most important developments in gene therapy, mRNA, CRISPR, and longevity medicine — explained in plain language for the people who need them most.
This week's edition
Moderna and Merck have built a cancer vaccine personalised to each patient's tumour. The results are unlike anything seen before.
In November 2025, fifteen patients received a single CRISPR infusion. Their cholesterol dropped, and stayed down.
In January 2026, the FDA cleared the first-ever human trial of a therapy that doesn't treat a disease — it reverses cellular age.
Pick your thread
1 story
Programmable medicine. From COVID vaccines to personalised cancer therapy — drugs that can be designed in days, not decades.
Read mRNA stories →1 story
One change, made once. CRISPR therapies edit DNA directly — turning chronic disease management into one-time treatment.
Read CRISPR stories →1 story
Treating ageing as a target. Cellular reprogramming and Yamanaka factors are entering human trials — changing what 'incurable' means.
Read longevity stories →The archive
About Gene Shot
We're a small editorial team translating medical research into language a person without a PhD can read at the kitchen table. No jargon. No hype. No false hope.
Most of what we cover is years from a clinic near you. Some is available now. We try to be precise about which is which.
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Three stories. Six minutes. The most important developments in unconventional medicine — explained plainly, for the people who need them.